10042

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10042

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Amphotericin B from Streptomyces sp.

BioChemika, ~80% (HPLC)

Synonym:Fungizone
CAS Number:1397-89-3
Linear Formula:C47H73NO17
Molecular Weight:924.08
Beilstein Registry Number:78342
EC Number:215-742-2
MDL number:MFCD00877763

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Description

Biochem/physiol ActionsPolyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out.
Antimicrobial spectrum: fungi and yeast.

Properties

product lineBioChemika
assay~80% (HPLC)
solubilityDMF: 1 M HCl (3:1): 50 mg/mL, clear to slightly turbid, orange to very deep red
storage temp.2-8°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-36
WGK Germany3
RTECSBU2625000

References

referencePerlman, D., Use of antibiotics in cell culture media. Meth. Enzymol. LVIII, 112, (1979)
MerckMerck 13,590
BeilsteinBeil. 18,V,10,525